Firstly, WBV at high shear stress was determined, from various possible pairs of haematocrit and total proteins, arithmetically according to validated formula: It is supported materially by the Albury South West Pathology – a unit of Western Pathology Cluster of NSW Health Australia. This work is part of Translational Biomedical Science Research initiative of the author. Another objective is to suggest normal, subnormal and critical reference ranges applicable to this method. However, a validated arithmetic method exists whereby WBV can be derived for any patient who has results for haematocrit and total serum proteins.īased on the arithmetic method for WBV from haematocrit (HCT) and serum total proteins (TP), the objective of this work is develop an algorithm in the form of a chart by which clinicians can easily extrapolate WBV values in their consulting rooms or on the ward. The implication is that not many clinicians are able to assess WBV when they want to. Moreover, while several methods for the assessment of WBV exist, not every pathology unit has equipment for any of the diverse methods. Considering the implication of stasis in metabolic diseases, such usage is under-utility. In current clinical practice, WBV is assessed mainly in the management of some diseases associated with critical hyperproteinaemia, polycythemia and retinal occlusion. Basically, increase in cell-cell or cell-macromolecule contacts leads to increase in friction and, by default, reduction in fluidity vis-à-vis increase in viscosity. Increase in WBV is subclinical risk factor for future cardiovascular disease.Factors that increase WBV include haematocrit, total plasma protein, erythrocyte aggregation and erythrocyte deformability. It is a property of the fluidity and internal friction of blood determined in part by adjacent fluidy blood cells as well as other constituents sliding past one another. It is an intrinsic resistance of blood flow in the vascular system. Specifically, WBV is the index for stasis. Whole blood viscosity (WBV) is one of Virchow's triad, which has been an established concept of three phenomena including stasis, endothelial dysfunction and atherothrombosis that ultimately lead to, and/or result from cardiovascular complications.Each phenomenon represents a subclinical vascular process, which in turn is indicated by a clinical pathology index.

Blood viscosity test normal range